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Figure 3


Fig. 3. Influence of VEGF on retinal ganglion cell differentiation. (A) Effects of VEGF concentrations on development of NF+ cells in E5-E7 explants in vitro (n=5). (B) Effects of sFLK1- and VEGF-producing cells on percentages of NF+ cells in vivo at E5. Black and white bars represent implanted and the contralateral non-implanted eyes, respectively (n=6; *P<0.03). (C-E) Immunostaining show effects of AP (C), sFLK1 (D) or VEGF (E) on Islet1/2+ cells in E5-E7 explants. Scale bars: 50 µm.





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