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Fig. 3. Inhibition of spore induction. (A) KP cells developing as
monolayers were treated with various concentrations of GABA and glutamate, and
the proportion of spores determined after 1 hour: 1 nM GABA (black circles),
10 nM GABA (triangles), 100 nM GABA (squares), 1 µM GABA (white circles).
Glutamate was added simultaneously with GABA at the concentrations indicated.
(B) SDF-2 was added to the cells at 0.1 pM (circles); 10 pM SDF-2
(triangles); 10 nM (squares). Glutamate was added simultaneously at the
concentrations indicated. (C) GABA and CGP 55845 were added at various
concentrations and the proportion of spores determined after 1 hour; 1 nM GABA
(black circles), 10 nM GABA (triangles), 100 nM GABA (squares), 1 µM GABA
(white circles). CGP 55845 was added simultaneously at the concentrations
indicated. (D) SDF-2 was added to the cells at 0.1 pM (circles); 10 pM
SDF-2 (triangles); 10 nM (squares). CGP 55845 was added simultaneously at the
concentrations indicated.
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