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Figure 2


Fig. 2. GFP+ cells in explants of hindgut (taken from RetTGM/+ embryos) maintained in control conditions or exposed to an L1 function blocking antibody for 18 hours. In the control explant, the cells are elongated and migrate in chains, except when undergoing cell division. After dividing, the daughter cells quickly become elongated and resume migration as a chain. When the activity of the cell-adhesion molecule L1 is perturbed, many solitary cells are observed (asterisks) that are round and do not migrate (Anderson et al., 2006). Image kindly provided by Richard Anderson and Heather Young (University of Melbourne, Melbourne, Australia).





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