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Figure 4


Fig. 4. APC2 mutant proteins lose cortical association. Germ-band-extended embryos stained for phosphotyrosine labeling the cortex (green), and APC2 (red). (A,A') Wild-type APC2 localizes to the cortex (arrow) and in the cytoplasm of the ectoderm. (B,C) Mutant proteins fall into two categories: (C) those with no detectable cortical localization (APC2g41 shown); and (B) those with some residual cortical localization (arrow; APC2N175K shown). Scale bar: 10 µm.





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