spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 6


Fig. 6. Loss of Tbx1 function specifically disrupts the expression of Fgf receptor 1 in the caudal pharyngeal arches. (A-C) Whole-mount in situ hybridized 35ss embryos of the indicated genotypes. Note the Tbx1 dose-dependent reduction in Fgfr1 expression in arches 3-6 (red arrowheads and bracket), and the preserved expression in arches 1 and 2, and the limb bud. This finding was consistent in 6/6 heterozygotes and mutants assayed. (D-E'') Sections reveal decreased Fgfr1 expression in unsegmented endoderm/mesenchyme of the mutant (red arrowheads) compared with the control (black arrowheads).





Right arrow Return to article