spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 3


Fig. 3. Manipulations in BDNF tectal levels influence PSD95-GFP labeled postsynaptic specializations on tectal neuron dendritic arbors. Image reconstructions of representative tectal neurons illustrate dendritic arbor complexity and synapse number 0, 24 and 48 hours after BDNF or anti-BDNF treatment. Individual neurons double labeled with PSD95-GFP and DsRed2 were visualized by confocal microscopy in live developing tadpoles after acute tectal injection of (A,B) control vehicle solution, (C) BDNF or (D) anti-BDNF. (A-D) Tectal neuron dendritic arbors become morphologically more complex over time. (C) In the BDNF-treated tadpoles, both the number and density of PSD95-GFP puncta per dendrite increased at 24 and 48 hours. (D) Anti-BDNF limited dendritic arbor growth and decreased PSD95-GFP puncta (see also Figs 4, 5). The arrow indicates the axonal process of the neuron. Scale bars: 20 µm.





Right arrow Return to article