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Fig. 5. The role of calderón activity in Minute
mediated cell competition. (A) Diagram depicting the induction of
Minute+ cald mutant clones (upper cell) and their
Minute- cald+ twins (lower cell) after a
mitotic recombination event. (B-G,I) Clones are marked by the
absence of the ß-Gal marker (grey). Twins are marked by the presence of
two copies of the ß-Gal marker (white). (B,D,F)
Minute+ control clones visualized 24 (B), 48 (D) and 72
(F) h after induction. Note all twin Minute- homozygous
clones have already disappeared 48 h after induction. (C,E,G,I) cald
Minute+ clones visualized 24 (C), 48 (E) and 72 (G,I) h after
induction. Some twins (Minute- homozygous and wild type
for cald function) are recovered even 72 h after induction (magnified
in I). (H) Graph plotting the ratio of
Minute-/Minute+ control clones (in black) and
the ratio of Minute-/Minute+ cald mutant clones
(in red). 24 h after clone induction: number of Minute+
clones: 522; number of Minute+ cald clones: 253. 48 h
after clone induction: number of Minute+ clones: 507;
number of Minute+ cald clones: 187. 72 h after clone
induction: number of Minute+ clones: 58; number of
Minute+ cald clones: 81.
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