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Figure 7


Fig. 7. Peripheral nerve development in Sox10Sox8ki/Sox8ki mice. (A-J) Immunohistological analysis of spinal nerves from wild-type (A,C,E,G,I) and Sox10Sox8ki/Sox8ki (B,D,F,H,J) embryos at 18.5 dpc was carried out using antibodies against NF-165 (A,B), Oct6 (C,D) and Krox20 (E,F). EGFP autofluorescence (G,H) and occurrence of Sox10 (I,J) was additionally visualized in both genotypes. (K-N) Immunohistochemistry on transverse sections of peripheral nerves from wild-type (K,M) and Sox10Sox8ki/Sox8ki (L,N) mice at postnatal day 3 using antibodies against MBP (K,L) and MPZ (M,N).





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