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Figure 1


Fig. 1. Wnt11 expression in the DML and Wnt6 expression in the ectoderm overlying the somites are mutually exclusive. (A,E) Whole-mount in situ hybridization of HH stage 15 chick embryos hybridized with Wnt6 (A) and Wnt11 (E) probes. (B-D) Transverse sections at different anteroposterior levels of the embryo shown in A. (B) Section at the level of an epithelial somite. Wnt6 expression in the ectoderm overlying the neural tube, the paraxial mesoderm and the lateral plate mesoderm. (C,D) The somite has compartmentalized and the dermomyotome and the sclerotome are visible. Wnt6 expression is restricted to the ectoderm overlying the lateral lip of the dermomyotome and the lateral plate mesoderm. (F-H) Transverse sections of the embryo shown in E at the AP levels indicated. At the level of the presomitic mesoderm (not shown) and the epithelial somite (F), Wnt11 is not expressed. Wnt11 expression starts after compartmentalization of the somite into dermomyotome and sclerotome, with strong expression in the dorsomedial lip of the dermomyotome (G,H).





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