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Figure 5


Fig. 5. Macrophages overexpressing dizzy leave long stable protrusions behind during their migration. The panels show time series of pictures taken from embryos expressing actin::gfp in the macrophages, at stage 13; numbers are minutes lapsed after the start of the series. The cells are located on the ventral side of the midline of the VNC (indicated by black line; anterior is to the left). (Top row) dizzyh.EP embryo; one of the cells (below asterisk) moves to the left edge of the VNC and maintains contact with the cells at the midline by a long cellular extension. (Bottom row) Wild-type embryo; one of the cells (asterisk) is followed along the midline and from there to the left edge of the VNC. Although the cell occasionally forms a short tail (20' panel), it does not maintain contact to cells it has passed on its path (pictures from Movies 1 and 2 in the supplementary material. Each panel represents 70 µm in width.





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