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Fig. 7. XHRT1 reverses the effect of Su(H)DBM on Evi1
but is not sufficient to restore XSMP-30 expression. (A-H)
Late tailbud/early tadpole stage embryos injected with 500 pg of
Su(H)DBM mRNA together with 500 pg of XHRT1a-mut-MT-hGR
mRNA, untreated (A-D) or dexamethasone treated (E-H) at stage 22.
ß-galactosidase RNA was co-injected to identify the injected side. Note
the decrease of XSMP-30 and the increase of Evi1 expression
in untreated embryos, and the reduction of both XSMP-30 and
Evi1 expression in treated embryos. (I) Quantification of the
results. Embryos were classified into two phenotypes (increase Evi1
and decrease XSMP-30). n, number of cases analysed.
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