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Figure 1


Fig. 1. Genomic organisation of the dfer locus. (A) In GAL4MZ465, pGawB (red) is inserted upstream of dfer (green). The deletions dfer{Delta}1 and dfer{Delta}ex1 are depicted (purple). (B) Exon structure of the four predicted dfer isoforms (a section of the third intron is deleted for clarity). Exon 1 is non-coding. Additional exons in dferRA and dferRD are in pink. (C) Predicted protein structure of DFer isoforms. (D) Molecular map of the dfergof locus. pGawB (red) has undergone a rearrangement, duplicating and inverting GAL4, and deleting pBluescript (pBS) and most of mini-white (mw+). (E) dfergof produces three transcripts, splicing the first exon of mini white (red) to exons of dfer (green). Light green exons are spliced out. (F) One transcript (wex1-DFerRB) is predicted to encode a White-DFer fusion protein.





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