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Figure 4


Fig. 4. The DYT1 gene structure and annotated conserved domain. (A) The genomic region of the DYT1 gene. The dyt1 insertion is flanked by a direct repeat of 6 bp ACTTCT, which correspond to nucleotides 109-104 upstream of the annotated ATG (nucleotides 1-3) codon. The DYT1 gene has three exons represented as white boxes. (B) The annotated amino acid sequence of the DYT1 protein, with 207 amino acid residues. From Phe29 to the Gln78 is the conserved bHLH domain, which corresponds to the black region in the schematic box image and is underlined in the amino acid sequence. (C) An unrooted neighbor-joining tree of Arabidopsis, rice, and Poplar bHLH genes in the same subfamily as DYT1. Gene ID numbers starting with `At' indicate genes from Arabidopsis thaliana; names of genes with functional information are given after the gene ID numbers. Gene ID numbers starting with `Os' indicates genes from rice (Oryza sativa); UDT1 is shown as OsUDT1. `Pt' indicates genes from poplar (Populus trichocarpa), with temporary names given according to gene ID from the Floral Genome Project. Bootstrap values are shown near the relevant nodes.





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