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Fig. 8. Osx1-GFP::Cre conditional stabilization of ß-catenin does not promote expression of osteocalcin. Histological analysis and in situ hybridization of an osteocalcin-specific anti-sense ³⁵S-labeled riboprobe to sections of E16.5 tibia from (A-E) Catnb^lox(ex3)/+ (wild type) and (F-J) Osx1-GFP::Cre;Catnb^lox(ex3)/+ (mutant) embryos. Arrows indicate sites of high osteocalcin expression in the wild type and low-level osteocalcin expression in the mutant in the periosteum.

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