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Figure 3


Fig. 3. Neurogenesis in wild-type and laminin {gamma}1III4-/- cortex. (A-H) E14 or E18 wild-type and laminin {gamma}1III4-/- cortex sections stained for the neuronal antigen ßIII-Tubulin or Math2 mRNA. Arrowheads in B and red arrows in H indicate neuronal ectopias in the subarachnoidal space, arrows in B indicate ectopic clusters of precursors in the laminin {gamma}1III4-/- cortex. The broken yellow and red lines in C delineate the cortical plate thickness in relation to the cortex thickness. Math2 expression is absent in the upper layers of the laminin {gamma}1III4-/- cortex (H), while these neurons still contain ßIII-Tubulin (F). Scale bars: 100 µm for A,B,E,F; 200 µm for C,D,G,H.





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