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Figure 5


Fig. 5. Proliferation and neurogenesis in {alpha}6 integrin-/- cortex. Micrographs of E14 wild-type and {alpha}6 integrin-/- cortex sections (A,B,E-H) stained as indicated. (C,D) Quantification of the number of PH3-positive cells in M phase per cortex area (C; wild type: n=39 sections, three animals, {alpha}6 integrin-/-: n=50, three animals) and of the percentages of cells dividing with horizontal, oblique or perpendicular orientation to the ventricular surface (D; wild type: n=89 mitoses, one animal, {alpha}6 integrin-/-: n=150, one animal) in wild-type and {alpha}6 integrin-/- cerebral cortex. Scale bars: 100 µm.





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