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Figure 7


Fig. 7. FGF signaling is required for induction of chordin by ß-catenin, Squint and Bozozok. chd and bmp4 expression in ichabod embryos (A,B) is restored to wild-type pattern by injection of ß-catenin RNA (C,F), sqt RNA (I,L), or boz RNA (O,R). Co-injection of XFD RNA inhibits induction of chd by ß-catenin (D), Sqt (J) and Boz (P), and dorsal repression of bmp4 by ß-catenin (G) and Sqt (M). However, repression of dorsal expression of bmp4 by Boz is observed in XFD RNA-injected embryos (S, compared with R and B). Co-injection with d50 RNA had no effect on ß-catenin, Sqt, or Boz functions (E,H,K,N,Q,T). Embryos are at 70% epiboly, shown in lateral view, dorsal to the right.





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