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Figure 3


Fig. 3. DE-cad requirements for ommatidial rotation. Tangential sections of adult eyes are shown (dorsal is upwards, anterior leftwards); associated bottom panels show schematic representations (arrows as in Fig. 1). (A) sevGal4; UAS-DE-cadDN (sev>DE-cadDN), a dominant-negative construct with two internally deleted CAD repeats, causes under-rotation. The under-rotation is enhanced by decreasing endogenous DE-cad/shg (B; sev>DEcadDN; shg-/+), and is suppressed by co-expression of full-length DE-cad (C; sev>DEcadDN;sev>DE-cadWT). (D) Decreasing endogenous Arm (armYD35/+, null allele) enhances under-rotation and adhesion defects of sev>DE-cadDN. (E) armXM19, an arm allele defective for Wg signaling, but functional for cell adhesion, does not modify the sev>DE-cadDN phenotype.





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