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Fig. 6. RhoA affects DE-cad function in rotation and localization. (A,B) Tangential sections of adult eyes of the following genotypes (anterior is leftwards and dorsal upwards). (A) Co-expression of sev>DEcadDN with UAS-GFP (control). (B) Co-expression of sev>DEcadDN with UAS-RhoA^IR. UAS-RhoA^IR enhances under-rotation associated with sev>DEcadDN (compare A with B). Arrows are as in Fig. 1. (C) Confocal microscopy image of DE-cad (magenta and C') localization in rhoA^72R clones (hypomorphic allele). DE-cad distribution within nascent ommatidial preclusters is disorganized, the overall DE-cad levels are reduced posterior to MF. Green: GFP labeling wild-type tissue.

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