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Fig. 3. Expression of primitive streak and AVE markers in wild-type and
ApcMin/Min embryos. In situ hybridization in 4.75 (A),
and 5.5 (B-L) dpc embryos. Double labeling with T and (A)
Pem, (B) Gsc or (C) Hex. (D-H) Single
labeling of Eomes (D), Otx2 (E), Fgf8
(F), Lhx1 (G), Cer1 (H), Snai1
(I), cripto (J), Nodal (K) and Foxa2
(L). The arrowhead in D indicates a labeled epiblast cell. Ep, epiblast; PE,
parietal endoderm; ExE, extraembryonic ectoderm.