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Fig. 4. PGC migration along the hindgut of Cx43
1KO embryos.Phase
contrast (A) and GFP fluorescence (B) images of an E9.5
wild-type mouse embryo demonstrate the distribution of PGCs along the hindgut.
We used somites as morphological landmarks (outlined in yellow) to assess the
abundance of PGCs along the hindgut. We also determined the maximal PGC
migration distance by measuring the distance from the base of the allantois
(arrowhead), where PGCs originate, to the migration front situated rostrally
along the anterior hindgut (arrow). Scale bars: 1 mm.