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Fig. 7. Disrupted morphology and inner structure of mitochondria in
DIC-1(RNAi) muscle cells observed by fluorescence microscopy and
cryo-electron microscopy. (A) The musculature of
dic-1(RNAi) worms shows abnormal morphology of active
mitochondria stained with Mitotracker Red. (B) The mitochondrial matrix
visualized with a mitochondrial matrix-targeting sequence::GFP construct
controlled by the myo-3 promoter. (C) Electron micrographs of
mitochondria (enclosed by brackets) in wild-type and
dic-1(RNAi) muscle cells. Scale bars: 10 µm in A; 5 µm
in B; 0.2 µm in C.
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