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Figure 4


Fig. 4. MES-4 is responsible for all H3K36me2 in early embryos, but another HMT becomes active by the ~40-cell stage. DNA is stained with PL4-2 (G,H) or PA3 (all other rows). P granules are stained with monoclonal antibody OIC1D4 (Hird et al., 1996). Arrows indicate P-granule-containing primordial germ cells. Anterior is to the left. (A,B) Wild-type and mes-4(bn73) four-cell embryos. (C,D) ~40-cell embryos. (E,F) ~100-cell embryos. (G,H) Three-fold embryos. Scale bar: 10 µm.





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