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Fig. 4. Gdf3 expression in pre-implantation and early post-implantation
mouse embryos. (A,B) Expression of Gdf3 is found at
low levels in the inner cells of compacted morula at the 16-cell stage (A),
and is later expressed at higher levels in the inner cell mass (icm) at the
blastocyst stage (B), with no expression in the trophoblast or primitive
endoderm (pe). (C-F) After implantation, expression is
restricted to the embryonic epiblast (epi) at 5.5 dpc (C,D) and 6.0 dpc (E,F),
and is not found in the visceral endoderm (ve) or extra-embryonic ectoderm;
expression disappears prior to primitive streak formation. Scale bars: 50
µm.
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