(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.

Fig. 6. Molecular analysis of the optic vesicle and infundibulum in
Raldh2-/- embryos. (A,B) Whole-mount
immunodetection of PAX6 protein in 10- to 11-somite stage (main panels) and
20- to 22-somite stage (insets) embryos. Profile views. Brackets indicate PAX6
expression in the dorsal telencephalon and diencephalon.
(C-D') PAX6 immunohistochemistry on frontal sections
through the optic vesicle (C,D) and telencephalon (C',D') of
wild-type and Raldh2-/- embryos (13-14 somites).
(E-L) Whole-mount in situ hybridization of Six3 (E,F),
Pax2 (G,H), Hesx1 (I,J) and Bmp4 (K,L) in 12- to
14-somite stage embryos. Genotypes are indicated above. Profile views. Insets
in E,F show frontal views of Six6-hybridized embryos (brackets
indicate infundibulum). Other insets show details of the optic vesicle of E9.5
embryos (G,H) or ventral views of the same embryos (I-L). ov, optic vesicle;
te, telencephalon.