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Fig. 1. Molecular characterization of Grip128 mutant alleles.
(A) Schematic overview of the Grip128 protein and the mutant alleles.
Motifs are indicated (Gunawardane et al.,
2000). C to T changes result in STOP codons replacing
Gln662 in Grip128326 and Gln706 in
Grip128352. (B) Wild-type and homozygous mutant
ovarian and male extracts were analyzed by western blotting with a Grip128
antibody (Gunawardane et al.,
2000). Grip128 is indicated by an arrow. Additional bands are
non-specific.