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Figure 5


Fig. 5. Meiosis is perturbed in Grip75 and Grip128 mutant spermatocytes. (A-C) Wild-type (A), Grip75175 (B) and Grip128352 (C) mutant spermatids at the onion stage. Nuclei appear bright in phase-contrast microscopy (arrowheads), whereas mitochondria are dark (arrows). (D-F) EM cross-sections of wild-type (D), Grip75175 (E) and Grip128352 (F) mutant sperm flagella. Scale bars: 500 nm. The arrowheads indicate axonemes, the arrows indicate mitochondria. (G-J) Meiosis I spindles at metaphase in wild-type (G), Grip75175 (H) and Grip128352 (J) mutant spermatocytes. Microtubules are shown in green, DNA is in red.





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