spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 6


Fig. 6. Polo overexpression restores BicDPA66 protein function during early oogenesis. (A,B) C(3)G is in red and BicD in green. (A) BicDPA66 ovariole with no cell in meiosis from stage 2b of the germarium, and diffuse localization of BicD. (B) BicDPA66 ovariole overexpressing Polo. Each follicle contains an oocyte in meiosis, which accumulates BicD. (C) DNA staining of later stage follicles in a BicDPA66 ovariole overexpressing Polo. Stage 4 and stage 6 follicles contain an oocyte marked by the presence of the condensed DNA (arrowheads). The follicle at stage 9 is degenerating. (D) Model of a positive feedback loop between Polo and BicD proteins during meiosis restriction and oocyte differentiation. The Polo kinase is required to trigger meiosis and to activate BicD-dependent transport. In turn, BicD is required for the transport of oocyte determinants and for Polo localization.





Right arrow Return to article