spacer gif spacer gif spacer gif spacer gif ARCHIVE ANNOUNCEMENT! spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 4


Fig. 4. fibronectin 1 expression is regulated by mtx1. fibronectin 1 gene expression and Fibronectin protein localization around the migrating myocardial cells were examined in embryos injected into the YSL with mtx1 MO(A) or mtx1 mRNA. (A-F) Anterior views, (G,H) Lateral views in the head region. (A-H) fibronectin 1 expression at the 14-(A,B; 16 hpf), 18-(E-H; 18 hpf), and 21-somite stages (C,D; 21.5 hpf). (A-D) fibronectin 1 expression appeared to be reduced in mtx1 MO(A)-injected embryos. (E-H) Conversely, fibronectin 1 expression appeared to be increased in mtx1 mRNA-injected embryos. (F,H) fibronectin 1 expression was upregulated mostly in embryonic tissues, even though mtx1 mRNA was injected into the YSL (red dots in H), indicating that mtx1 regulates fibronectin 1 expression in a non-cell-autonomous manner. (I-K) Transverse sections of cmlc2:GFP (false colored blue) transgenic embryos immunostained for ß-catenin (red) and Fibronectin (green). Fibronectin deposition appeared to be decreased in mtx1 MO-injected embryos (J), whereas it appeared to be increased in mtx1 mRNA-injected embryos (K) specifically in embryonic tissues.





Right arrow Return to article