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Fig. 5. Mosaic analysis for egl-38 function. (A) Cell
lineage chart of the early cell divisions in C. elegans, indicating
the embryonic source of the cells listed below, which were assayed in mosaic
animals (see Sulston et al.,
1983). An `x' indicates that the cells derive from more than one
cell in the lineage. (B) Summary of the observations from mosaic
animals, grouped according to category. For clarity, the mosaic animals were
classified as wild type if they exhibited five or fewer corpses per gonad arm,
and classified as mutant if they exhibited six or more corpses per gonad arm
(beyond two standard deviations from the average of animals with the transgene
present in all lineages). See text for additional analysis. All animals
lacking the transgene in their offspring were classified as P4-negative. A
more stringent analysis of germline loss (including in the analysis only
animals that lack the transgene in D as well as P4 but retain the transgene in
some other somatic lineages) yields a slightly lower, but similar proportion
of animals classified as wild type (11 of 18, or 61%).
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