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Fig. 5. Profilin1 is required for Daam1-mediated stress fiber induction.
(A) Expression of Myc-tagged C-Daam1 (red) in NIH3T3 cells induces
stress fibers (green), and this effect is abrogated by coexpression of
Profilin1 siRNA but not GFP siRNA, magnifications of the boxed areas (white)
are shown at the side of each respective panel. (B) Quantification of
the effects on Profilin1 and GFP siRNA on stress fiber formation induced by
C-Daam1 expression in NIH3T3 cells. Number of cells evaluated is shown at the
top of each bar.
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