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Figure 4


Fig. 4. DPPIV- and OV6-positive bile ducts in DPPIV-host rat livers transplanted with CMP-FLEC. (A,B) Acetone fixed frozen sections prepared from host rat liver at 9 months after transplantation of CMP-FLECIV (isolate P, Table 1) were labeled with MAbs specific for OV6, a bile duct marker (red) and enzymatically active DPPIV (green) by double IIF protocol. A collection of donor-derived DPPIV+/OV6+ bile ducts (arrows, B) located between two colonies of DPPIV+ hepatocytes with strong canalicular staining patterns (arrows, A). (B) A high magnification view of the area enclosed by the rectangle in A. Scale bars: 100 µm.





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