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Figure 9


Fig. 9. Differentiation of OBSC into dopaminergic and mitral/tufted neurons. (A-D) Representative images of MAP2ab+ and Th+ cells in differentiating E13.5 OBSC cultures. (E) Average percentages of Th+ neurons relative to total MAP2ab+ neurons. Results are the mean±s.e.m. of data from four cultures in two experiments. Scale bar: in D, 40 µm. (F) Average percentages of Tbr1+ vs total MAP2ab+ neurons. Bdnf-treated cultures had 26% more Tbr1-labeled cells than controls (not statistically significant). Results are the mean±s.e.m. of data from four to six cultures in three experiments. (G-J) Representative images of MAP2ab+ and Tbr1+ cells. Arrows show Tbr1+ nuclei in the neurons. Scale bar in J: 50 µm.





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