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Figure 5


Fig. 5. Wnt-Fz signalling controls anterior-directed projections of mechanosensory neurons in C. elegans. (A) In the 2-fold stage C. elegans embryo, egl-20(wnt) is expressed (red shading) in the tail behind anterior (AVM) and posterior (PVM) ventral mechanosensory neurons. (B) The position and projections of the different mechanosensory neurons of the worm (only one of the ALM and PLM bilateral pairs is shown; PVM and AVM are positioned on opposite hemi-sides of the embryo). (C) In double Wnt (cwn-1;egl-20)mutants or double Fz (mig-1; mom-5) mutants, the anterior projection of the AVM and PVM axons is impaired. Similarly, ALM axons do not branch in the nerve ring.





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