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Fig. 7. Muscle stimulation prevents loss of recycled AChRs from denervated
NMJs. Three days after labeling with BTX-biotin/strept-488, recycled AChRs
on denervated muscle were labeled with strept-594 and imaged immediately, and
then again after 8 hours in the absence (A) and presence (B) of
stimulation. Scale bar, 20 µm. (C) Graph summarizing the
fluorescence measurements obtained from many synapses. After 8 hours, 
66%
of fluorescence from recycled receptors remained in denervated synapses;
however, when denervated muscle was chronically stimulated, this loss of
fluorescence was largely abolished.
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