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Figure 5


Fig. 5. max-2;pak-1 double mutants are phenotypically similar to unc-73 and double rac mutants. (A-D) Representative morphology of the DD and VD neurons in unc-73, rac and PAK mutants. Arrows point to displaced VD neurons and open arrowheads point to abnormal commissures. (A) A wild-type animal. (B) An unc-73(e936)I animal. (C) A ced-10(n1993)IV;mig-2(mu28)X animal. (D) A max-2(cy2)II;pak-1(ok448)X animal. (E) DD and VD commissural guidance defects in PAK mutants. (F) P cell migration defects in PAK, rac and unc-73 mutants. The numbers (n) of animals used for each experiment are shown; bars represent the standard error in E,F. All animals are in the oxIs12[Punc-47::GFP]X. Scale bar: 10 µm.





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