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Fig. 5. bchs mutations suppress bristle defects of rab11 mutants. (A) Portions of posterior abdomens from indicated genotypes. In control, each socket contains a bristle (microchaete), but in rab11^ex1/rab11^93Bi many sockets are empty. Mutation of one copy of bchs (bchs^17/+;rab11^ex1/rab11^93Bi) restores many bristles, while mutation of both copies of bchs (bchs¹⁷/bchs¹²;rab11^ex1/rab11^93Bi) restores all bristles. Arrowheads indicate bristle-filled or empty sockets in the last row of the third abdominal tergite (segment). (B) Portions of posterior scutellum from indicated genotypes. Posterior scutellar bristles are shortened in rab11^ex1/rab11^93Bi. Bristle length is restored partially by one mutant copy of bchs (bchs¹⁷/+;rab11^ex1/rab11^93Bi) and more fully by homozygosity for bchs (bchs¹⁷/bchs¹²;rab11^ex1/rab11^93Bi). (C) Quantitation of abdominal bristle loss. The fraction of sockets containing bristles was calculated for the last row of abdominal tergites 2, 3 and 4. Error bars are s.e.m. Df is Df(2L)cl7, a chromosome deleted for bchs. Top panel: reduction of bchs gene dosage suppresses bristle loss of rab11^ex1/rab11^93Bi. n10 for each genotype, P<0.0001 for all genotypes compared to rab11^ex1/rab11^93Bi. Bottom panel: reduction of bchs gene dosage suppresses bristle loss of rab11^93Bi homozygotes. n10 for each genotype, P<0.0001 for all genotypes compared to rab11^93Bi/rab11^93Bi. Scale bars: 30 µm in A; 50 µm in B.

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