|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 5. Gradients of Fgf and RA signals. (A-P) Expression of
fgf3 (A-D), fgf8 (E-H), raldh2 (I-L) and
cyp26a1 (M-P) in wild-type control (A,E,I,M), cdx1a morphant
(B,F,J,N), cdx4 morphant (C,G,K,O) and cdx1a/4 morphant
(D,H,L,P) embryos at 13 hpf. The posterior end of the embryos are marked by
arrowheads (I-L). (Q) Expression of fgf8 (red) and
krox20 (purple) in the trunk region of cdx4 morphant embryos
at 22 hpf. The ectopic krox20 in neural tissue and fgf8 in
somitic mesoderm are marked by a black arrowhead and red arrows, respectively.
(R-T) Schematic presentation of the Fgf and RA signaling gradients in
wild-type (R), cdx4 morphant (S) and cdx1a/4 morphant (T)
embryos. The expression domains of the fgfs and raldh2 are
indicated in red and green, respectively, in the body of each schematic. The
gradients of the Fgf and RA signals in the neuroectoderm are also indicated in
red and green, respectively, and shown to the right of each schematic. The
solid red bars on the right in R and S indicate stripes of Fgf signaling (see
Q). Scale bars: 100 µm.
|
