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Figure 5


Fig. 5. Cell death in the L-mutant eye is due to ectopic induction of Wg. (A-A''') The LOF clones of L on the ventral eye margin (A, arrow), posterior to MF and marked by the loss of GFP reporter (A', arrow), show ectopic induction of Drice (A'', arrow), coincident with the ectopic induction of Wg (A''', arrow). (B,C) LOF clones of L, generated by the MARCM approach, are positively marked by the GFP reporter and accompanied by the overexpression of SggS9A (B) or dTCFDN (C) to abolish Wg signaling in the eye. Notice that LOF clones of L in the ventral eye can no longer eliminate eye pattern (arrowheads).





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