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Figure 6


Fig. 6. Normal expression of retinogenic bHLH factors in Bhlhb5-null retinas. (A-F) Immunolabeling shows a largely overlapping expression of Bhlhb5 (green) and NeuroD (red) in E13 wild-type retina. B, D and F show the enlarged view of the corresponding boxed regions in A, C and E, respectively. (G,L) Anti-NeuroD labeling reveals no change in NeuroD expression in Bhlhb5-null retinas at E13. (H-K,M-P) Similarly, the expression of Math3 (H,M), Ngn2 (I,N), Math5 (J,O) and Mash1 (K,P) is unaffected in Bhlhb5-null retina at E14.5 as assessed by in situ hybridization. Scale bars: 100 µm.





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