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Figure 7


Fig. 7. Axon guidance defects associated with Daw signaling pathway components. (A) Representative axon guidance defects in a ventral muscle field of a stage 17 dawex11/dawex11 embryo. Defects are indicated with red arrows; black arrows indicate wild-type-like projections. (B) CNS and (C) SNa defects in dawex11/dawex11 embryos. (D) 12/13 synapse in dawex11/dawex11 third-instar larvae. (E) SNa and (F) SNb in stage 17 babo52/babo32 embryos derived from babo52 germline clones. (G) Ventral muscle field in 17 put heteroallelic embryos reared at 23.5°C. (H) SNa and (I) SNb in CNS of stage 17 Smad2 embryos derived from germline clones. (J) Quantification of loss-of-function defects for Daw signaling pathway components. Dorsal is up and anterior is left in all images. Scale bars: 100 µm in D; 50 µm in all others.





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