spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 6


Fig. 6. Effect of uri-1 depletion on meiotic cells. (A) Loss of uri-1 sensitizes meiotic germ cell to apoptosis. Apoptotic germ cell corpse numbers in the heterozygous uri-1 mutant and uri-1(RNAi)P0 animals (n=40 each) reveal a gla phenotype, which is completely suppressed by mutations in the apoptotic pathway components ced-3(lf)and ced-9(gf) (*P=3.0x10-20, #P=2.3x10-19). Error bars represent s.d. (B) Apoptotic germ cell corpse counts in wild-type and cep-1 germlines of uri-1(RNAi)P0 and control animals (n=40 each) reveal that the gla phenotype that is associated with loss of URI-1 is completely suppressed by loss of the DNA damage sensor p53 (C. elegans cep-1). Error bars represent s.d.





Right arrow Return to article