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Figure 5


Fig. 5. P2-receptor-evoked cytosolic Ca2+ signals in neurospheres derived from P2Y1-receptor knockout mice (C57BL/6J). The relative agonist potency in neurospheres from C57BL/6J wild-type mice corresponds to that of C57BL/6N mice (compare with Fig. 2B). In neurospheres derived from P2Y1-knockout mice, the ATP and UTP responses were equal and ADP and UDP were essentially inactive (mean±s.d., n=20-38).





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