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Figure 2


Fig. 2. Xena colocalizes with components of integrin adhesion complexes at intersomitic and intermyotomal junctions. Confocal images of stage 22 (A-C,G-I,M-O) and stage 35 (D-F,J-L) embryos stained for Xena (A,D,G,J,M; red in C,F,I,L,O), ß1-integrin (B,E, green in C,F), vinculin (H,K, green in I,L) and FAK (N, green in O). Xena colocalizes with ß1-integrin, vinculin and FAK at intersomitic boundaries and with ß1-integrin and vinculin at intermyotomal junctions (co-localization appears yellow). Xena staining was performed with anti-Xena antibodies. Anterior is to the left in all images. Scale bars: 100 µm.





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