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Figure 5


Fig. 5. CDK-1 depletion suppresses the infertility of WEE-1.3-depleted animals. (A-D) DIC images of uteri from wild-type (A), CDK-1-depleted (B), WEE-1.3-depleted (C), and co-depleted (D) adult hermaphrodites. Wild-type animals have embryos of all stages (A), whereas CDK-1-depleted animals contain only one-cell arrested embryos (B). WEE-1.3-depleted animals have uteri containing unfertilized `mushy' oocytes (C), whereas the co-depleted animals contain only one-cell arrested embryos (D). Embryos are ~50 µm in length. (E,F) Quantitation of (E) pH3- and (F) NOP1-positive nuclei by oocyte position in the proximal gonad. Below each graph is a table showing the number of oocytes analyzed for each RNAi condition.





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