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Figure 5


Fig. 5. Ft regulates PD wing growth and pattern. (A,B) Expression of Dll (red) and Wg (green) in wild-type (A) and in ftfd mutant (B) wing imaginal discs. Dll is upregulated in the ft mutant discs (B). (C,C') In the posterior (P) wing compartment displaying overexpression of Ft (UAS-ft/en-Gal4), Dll (red in C, grey in C') is downregulated when compared with its anterior (A) compartment or with that of a wild-type counterpart (also see Fig. 8H); the broken line (C') indicates the AP boundary. (D,D') A large ft422 clone, marked by loss of GFP (green), displays upregulated Q-vg-lacZ (red in D and grey in D'). (E) A plot of the intensity of Q-vg-lacZ expression over the wing pouch region (along the red broken line in D') to reveal upregulation of Q-vg-lacZ in the mutant clone along the PD axis. (F,G) Adult wing of a wild type (F) and of genotype en-Gal4/UAS-ft (G). Wing growth along the PD axis in the posterior compartment is truncated (G), as revealed by the close proximity of the anterior and posterior crossveins (arrowheads); AP boundary is indicated by broken lines.





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