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Fig. 1. Expression of Fez during mouse development. (A-K)
Expression of Fez at E8.0 (A), E8.5 (B), E9.5 (C), E10.5 (D), E12.5
(E-I) and E15.5 (J,K). (A-D) Whole-mount in situ hybridization, lateral views
with anterior to the left. (E-K) In situ hybridization of coronal sections
from the anterior (E) to the posterior (H), and coronal sections of the
olfactory epithelium (I-K) and the olfactory bulb (K). Fez
transcripts were detected in the olfactory epithelium (black arrowheads;
E,I,J,K), septum (black arrow, E), roof of the telencephalon (F), hypothalamus
(asterisks; G,H), prethalamus (black arrowhead, G) and amygdala (black arrows;
G,H), but not in the olfactory bulb (black arrows in K). (I)
High-magnification view of the olfactory epithelium. Fez expression
was detected in the olfactory epithelium, but was scarce in the vomeronasal
organs (VNO, white arrowheads in E,I).
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