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Fig. 3. Abnormal morphology of the olfactory bulb in Fez-deficient
mice. (A) The olfactory bulbs were smaller and farther apart in
Fez-deficient embryos (right) than in wild-type embryos (WT, left),
at P0. (B-E) Nissl staining of sagittal sections of the head region of
E14.5 (B,C) or E18.5 (D,E) wild-type (B,D) and Fez-deficient (C,E)
embryos; anterior to the right. Scale bars: 0.5 mm. (F-I) Nissl
staining of coronal sections of olfactory bulbs from E14.5 (F,G) or E18.5
(H,I) wild-type (F,H) and Fez-deficient (G,I) mice; medial to the
right. The olfactory bulb was smaller in Fez-deficient embryos than
in wild-type embryos at E18.5 and P0. An irregular formation of the mitral
cell layer (arrows, D,H,I) was detected in Fez-deficient embryos at
E18.5.
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