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Fig. 7. smo and tkv signaling affect pMAPK and Atonal
expression. Third instar eye-imaginal discs with mutant null clones
(outlined); anterior to the right; all to the same scale as indicated in L.
Genes homozygous in the clones are indicated on the left, antigens/stains
above; arrowheads indicate the furrow. (A-D) smo null clones
showing reduced Atonal and pMAPK expression (asterisk). Note, residual Atonal
is strongest in the lone R8 cells (arrow in B,D). (E-H) tkv
null clones showing of Atonal and pMAPK (arrows). (I-L) smo
tkv double-mutant clone in which Atonal and pMAPK expression is lost
(asterisk).