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Figure 6


Fig. 6. Contribution of cells of the Ngn3+ and Ngn3- lineages to functional spermatozoa. (A) Experimental design. Ngn3/Cre;CAG-CAT-Z double-transgenic male mice were mated with non-transgenic females, and the offspring genotyped to determine whether the contributed spermatozoa carried an intact (CAG-CAT-Z) or recombined (CAG-Z) form of the reporter gene. (B) Frequency of offspring with the intact (gray) and recombined (white) forms of the reporter gene, classified according to the paternal age at fertilization.





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